邓国刚
邮箱:ggdeng@ynu.edu.cn
职称:副研究员(硕士生导师)
地址:伟德国际1946源于英国呈贡校区伟德BETVlCTOR1946,国家重点实验室1栋1320
教育经历
2013.09-2019.07,伟德国际1946源于英国,有机化学,理学博士
2009.09-2013.07,昆明学院,化学,理学学士
工作经历
2022.01-至今, 伟德国际1946源于英国,伟德BETVlCTOR1946,教育部自然资源药物化学重点实验室,副研究员
2019.07-2021.07,伟德国际1946源于英国,化学科学与工程学院,博士后
研究领域
1) 有机合成方法学:主要研究2-氮杂烯丙基化合物作为超电子供体引发的自由基偶联反应,以此构建新的碳碳键及碳杂键。
2) 药物化学方向研究:以天然产物结构修饰来制备抗肿瘤活性分子的研究。
奖励荣誉和学术任职
云南省研究生优秀科技创新成果奖,2019
云南省优秀博士学位论文,2021
伟德国际1946源于英国东陆青年学者引进人才,2022
执教课程与教学成果
主讲《分析化学实验》,《药物分析与仪器分析实验》
科研项目
1) 云南省基础研究计划青年项目,N-苄基亚胺作为小分子催化剂合成酰基吡啶的反应研究, 2023.06-2026.05,主持
2) 伟德国际1946源于英国引进人才启动项目,2022.01-2027.12,主持
代表性论文
1) Deng, Guogang; Duan, Shengzu; Wang, Jing; Chen, Zhuo; Liu, Tongqi; Chen, Wen; Zhang, Hongbin*; Yang, Xiaodong*; Walsh, Patrick J. *, Transition-metal-free allylation of 2-azaallyls with allyl ethers through polar and radical mechanisms. Nature Communications, 2021, 12(1): 3860. (IF = 17.694,中科院I区Top)
2) Deng, Guogang; Li, Minyan; Yu, Kaili; Liu, Chunxiang; Liu, Zhengfen; Duan, Shengzu; Chen, Wen; Yang, Xiaodong*; Zhang, Hongbin*; Walsh, Patrick J *, Synthesis of benzofuran derivatives through cascade radical cyclization/intermolecular coupling of 2-azaallyls. Angewandte Chemie International Edition, 2019, 58(9): 2826-2830. (IF = 16.823,中科院I区Top)
3) Deng, Guogang; Zhou, Bei; Wang, Jing; Chen, Zhuo; Gong, Liang; Gong, Yaxiao; Wu, Dongmei; Li, Yan*; Zhang, Hongbin*; Yang, Xiaodong*, Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives. European Journal of Medicinal Chemistry, 2019, 168: 232-252. (IF = 7.088,中科院I区Top)
4) Yonggang Jiang; Bijun Wang; Dongxiang Liu, Dazhen Xia, Zhengfen Liu, Liang Li, Guogang Deng*; Xiaodong Yang*, Aryl acrylonitriles synthesis enabled by palladium-catalyzed α-alkenylation of arylacetonitriles with vinyl halides/triflates. Frontiers in Chemistry, 2022, 10, 1091566. (IF = 5.545,中科院三区)
5) Duan, Shengzu; Deng, Guogang; Zi, Yujin; Wu, Xiaomei; Tian, Xun; Liu, Zhengfen; Li, Minyan; Zhang, Hongbin*; Yang, Xiaodong*; Walsh, Patrick J.*, Nickel-catalyzed enantioselective vinylation of aryl 2-azaallyl anions. Chemical Science, 2021, 12(18): 6406-6412. (IF = 9.969,中科院I区Top)
6) Li Minyan; Berritt Simon; Matuszewski Lucas; Deng Guogang; Pascual Escudero Ana; Panetti Grace B; Poznik Michal; Yang Xiaodong; Chruma Jason J; Walsh Patrick J.*; Transition-metal-free radical C(sp(3))-C(sp(2)) and C(sp(3))-C(sp(3)) coupling enabled by 2-azaallyls as super-electron-donors and coupling-partners. Journal of the American Chemical Society, 2017, 139(45):16327-16333. (IF = 16.383,中科院I区Top)
7) Kaili Yu; Minyan Li; Guogang Deng; Chunxiang Liu; Jing Wang; Zhengfen Liu; Hongbin Zhang; Xiaodong Yang*; Patrick J. Walsh*, An efficient route to isochromene derivatives via cascade radical cyclization and radical-radical coupling. Advanced Synthesis & Catalysis, 2019, 361, 4354– 4359. (IF = 5.981,中科院二区)
8) Jing Wang; Guogang Deng; Chunxiang Liu; Zhuo Chen; Kaili Yu; Wen Chen; Hongbin Zhang*; Xiaodong Yang*, Transition metal-free synthesis of α-aminophosphine oxides through C(sp3)–P coupling of 2-azaallyls. Advanced Synthesis & Catalysis, 2020, 362, 2268–2273. (IF = 5.981,中科院二区)